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PON3 Rekombinanter Antikörper

PON3 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242035D11

Kat-Nr. : 84604-4-PBS

Synonyme

Paraoxonase 3 , Paraoxanase-3, EC:3.1.8.1, 242035D11

Filter:
  • Western Blot (WB) analysis of various lysates using PON3 Recombinant antibody (84604-4-RR)

    WB analysis using 84604-4-RR (same clone as 84604-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84604-4-RR (PON3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84604-4-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using PON3 Recombinant antibody (84604-4-RR)

    IHC staining of mouse liver using 84604-4-RR (same clone as 84604-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 84604-4-RR (PON3 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84604-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84604-4-RR

    Affinity and Kinetic Characterization of 84604-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84604-4-RR against Human PON3 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

84604-4-PBS bindet in WB, IHC, Indirect ELISA PON3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PON3 fusion protein Ag36602
Vollständiger Name paraoxonase 3
Berechnetes MolekulargewichtNM_000940.2 40kDa，354aa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerNM_000940.2
Gene symbol PON3
Gene ID (NCBI) 5446
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PON3, a member of the paraoxonase family, is expressed primarily in the liver and encodes a protein that is secreted into the bloodstream and binds to high-density lipoprotein (HDL). It also rapidly hydrolyzes lactones and inhibits the oxidation of low-density lipoprotein (LDL), thereby slowing the onset and progression of atherosclerosis. In addition, PON3 is closely associated with hepatocellular carcinoma (HCC), and is a potential therapeutic target for HCC by inducing cell cycle arrest and further inhibiting HCC cell proliferation.