PPARGC1B Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

PPARGC1B Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (4)

Anwendung

WB, CoIP, ELISA

Konjugation

Unkonjugiert

Publikationen(17)

Kat-Nr. : 22378-1-AP

Synonyme

ERRL1, PERC, PGC 1 beta, PGC 1(beta), PGC1, PGC1B, PPAR gamma coactivator 1 beta, PPARGC 1 beta, PPARGC1, PPARGC1B

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  WB analysis using 22378-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 22378-1-AP (PPARGC1B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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  IP experiment of mouse liver using 22378-1-AP

  IP result of anti-PPARGC1B (IP:22378-1-AP, 4ug; Detection:22378-1-AP 1:300) with mouse liver tissue lysate 4000ug.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HEK-293-Zellen, Rattenlebergewebe, SH-SY5Y-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 2 publications below
• WB: See 16 publications below
• CoIP: See 1 publications below

Produktinformation

22378-1-AP bindet in WB, CoIP, ELISA PPARGC1B und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Fisch, Hausschwein, Maus, Ziege, Riesenscheibenbrasse (Megalobrama amblycephala)
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PPARGC1B fusion protein Ag17566
• Vollständiger Name: peroxisome proliferator-activated receptor gamma, coactivator 1 beta
• Berechnetes Molekulargewicht: 1023 aa, 113 kDa
• Beobachtetes Molekulargewicht: 100-110 kDa
• GenBank-Zugangsnummer: BC132971
• Gene symbol: PPARGC1B
• Gene ID (NCBI): 133522
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Publikationen

Species	Application	Title
mouse	WB	Redox Biol; miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation; Authors - Xiaofei Wang
mouse	CoIP	Br J Pharmacol; Andrographolide prevents bone loss via targeting ERRalpha-regulated metabolic adaption of osteoclastogenesis.; Authors - Tongling Huang
mouse	WB	EMBO Rep; Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis.; Authors - Lei Liu ; KD Validated
Goat	WB	J Anim Sci Biotechnol; miR-25 modulates triacylglycerol and lipid accumulation in goat mammary epithelial cells by repressing PGC-1beta.; Authors - Liuan Ma
mouse	WB	Nutrients; Novel Choline-Deficient and 0.1%-Methionine-Added High-Fat Diet Induces Burned-Out Metabolic-Dysfunction-Associated Steatohepatitis with Inflammation by Rapid Immune Cell Infiltration on Male Mice; Authors - Takatoshi Sakaguchi
mouse	WB	FASEB J; Hypolipidemic effect of oleanolic acid is mediated by the miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice.; Authors - Siyu Chen ; KD Validated