CXCL7/PPBP Polyklonaler Antikörper

CXCL7/PPBP Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13313-1-PBS

Synonyme

PPBP,NAP2, CXCL7, NAP-2, PPBP, PPBP/NAP2

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  WB analysis of mouse liver using 13313-1-AP (same clone as 13313-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 13313-1-AP (PPBP,NAP2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human plasma using 13313-1-AP (same clone as 13313-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 13313-1-AP (PPBP,NAP2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human liver using 13313-1-AP (same clone as 13313-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 13313-1-AP (PPBP,NAP2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse placenta using 13313-1-AP (same clone as 13313-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse placenta tissue slide using 13313-1-AP (CXCL7/PPBP antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 13313-1-AP (same clone as 13313-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 13313-1-AP (CXCL7/PPBP antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13313-1-PBS bindet in WB, IHC, Indirect ELISA CXCL7/PPBP und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CXCL7/PPBP fusion protein Ag4147
• Vollständiger Name: pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
• Berechnetes Molekulargewicht: 128 aa, 14 kDa
• Beobachtetes Molekulargewicht: 8-14 kDa
• GenBank-Zugangsnummer: BC028217
• Gene symbol: PPBP
• Gene ID (NCBI): 5473
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PPBP, also named as CXCL7, NAP2, or β-Thromboglobulin, is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.