PPIL1 Rekombinanter Antikörper
PPIL1 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
250902G7
Kat-Nr. : 86312-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
86312-1-PBS bindet in WB, Indirect ELISA PPIL1 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | PPIL1 fusion protein Ag7436 |
| Vollständiger Name | peptidylprolyl isomerase (cyclophilin)-like 1 |
| Berechnetes Molekulargewicht | 18 kDa |
| Beobachtetes Molekulargewicht | 18 kDa |
| GenBank-Zugangsnummer | BC003048 |
| Gene symbol | PPIL1 |
| Gene ID (NCBI) | 51645 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Peptidyl-prolyl isomerase (PPIase) catalyzes the interconversion of a specific Pro-imide bond between the cis and trans conformations. PPIL1 (Peptidyl-prolyl cis-trans isomerase-like 1) is up-regulated in human colon cancer cells and an siRNA-mediated knockdown of PPIL1 resulted in a reduced number of viable cell (PMID: 20368803). Expression of PPIL1 was shown to be ubiquitous across all adult tissues (with highest expression in the adrenal gland, testis and heart). PPIL1 is also known to participate in the spliceosome; a complex and dynamic protein and RNA complex responsible for splicing introns from pre-mRNA (PMID: 33220177, 8978786).

