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PPM1K Polyklonaler Antikörper

PPM1K Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14573-1-PBS

Synonyme

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  • Western Blot (WB) analysis of human brain tissue using PPM1K Polyclonal antibody (14573-1-AP)

    WB analysis of human brain using 14573-1-AP (same clone as 14573-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 14573-1-AP (PPM1K antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14573-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human heart tissue using PPM1K Polyclonal antibody (14573-1-AP)

    WB analysis of human heart using 14573-1-AP (same clone as 14573-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 14573-1-AP (PPM1K antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14573-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human gliomas tissue using PPM1K Polyclonal antibody (14573-1-AP)

    IHC staining of human gliomas using 14573-1-AP (same clone as 14573-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas using 14573-1-AP (PPM1K antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14573-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human gliomas tissue using PPM1K Polyclonal antibody (14573-1-AP)

    IHC staining of human gliomas using 14573-1-AP (same clone as 14573-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas using 14573-1-AP (PPM1K antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14573-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14573-1-PBS bindet in WB, IHC, Indirect ELISA PPM1K und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PPM1K fusion protein Ag5660
Vollständiger Name protein phosphatase 1K (PP2C domain containing)
Berechnetes Molekulargewicht 41 kDa
Beobachtetes Molekulargewicht30-40 kDa
GenBank-ZugangsnummerBC037552
Gene symbol PPM1K
Gene ID (NCBI) 152926
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protein phosphatase, Mg2+/Mn2+ dependent 1K (PPM1K), is a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. PPMiK, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.PPM1K is essential for the regulation and nutrient-induced activation of the branched-chain alpha-keto acid dehydrogenase complex (BCKD or BCKDC), which catalyzes the breakdown of branched-chain amino acids (BCAA).