PPME1 Rekombinanter Antikörper

PPME1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242929H5

Kat-Nr. : 85221-5-PBS

Synonyme

242929H5, EC:3.1.1.89, PME 1, PME1, PME-1

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  WB analysis using 85221-5-RR (same clone as 85221-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85221-5-RR (PPME1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85221-5-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85221-5-PBS bindet in WB, Indirect ELISA PPME1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: PPME1 fusion protein Ag5817
• Vollständiger Name: protein phosphatase methylesterase 1
• Berechnetes Molekulargewicht: 42 kDa
• Beobachtetes Molekulargewicht: 44 kDa
• GenBank-Zugangsnummer: BC050705
• Gene symbol: PPME1
• Gene ID (NCBI): 51400
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PPME1 (Protein phosphatase methylesterase 1) is a protein phosphatase 2A (PP2A)-specific methyl esterase that negatively regulates PP2A through demethylation at its carboxy terminal leucine 309 residue (PMID: 24253382). PPME1 plays an important role in the development of cancers and may be a biomarker for pancreatic carcinoma, gastric and lung cancer (PMID: 32351291).