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PPP1R17 Polyklonaler Antikörper

PPP1R17 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27976-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using PPP1R17 Polyclonal antibody (27976-1-AP)

    WB analysis using 27976-1-AP (same clone as 27976-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27976-1-AP (C7orf16 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27976-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using PPP1R17 Polyclonal antibody (27976-1-AP)

    IF Staining of U2OS using 27976-1-AP (same clone as 27976-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using PPP1R17 antibody (27976-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27976-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using PPP1R17 Polyclonal antibody (27976-1-AP)

    IF Staining of U2OS using 27976-1-AP (same clone as 27976-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using PPP1R17 antibody (27976-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27976-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27976-1-PBS bindet in WB, IF/ICC, Indirect ELISA PPP1R17 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PPP1R17 fusion protein Ag15187
Vollständiger Name chromosome 7 open reading frame 16
Berechnetes Molekulargewicht 155 aa, 18 kDa
Beobachtetes Molekulargewicht 20-30 kDa
GenBank-ZugangsnummerBC028094
Gene symbol PPP1R17
Gene ID (NCBI) 10842
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PPP1R17, an endogenous substrate for cGMP-dependent protein kinase, exists almost exclusively in cerebellar Purkinje cells, where it is possibly involved in the induction of long-term depression (PMID: 10051666). PPP1R17 inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes. Allelic variants increase susceptibility to hypercholesterolemia (PMID: 12955585).