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PPP1R3C Polyklonaler Antikörper

PPP1R3C Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29424-1-PBS

Synonyme

PP1 subunit R5, PPP1R5, Protein targeting to glycogen

Filter:
  • Western Blot (WB) analysis of various lysates using PPP1R3C Polyclonal antibody (29424-1-AP)

    WB analysis using 29424-1-AP (same clone as 29424-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29424-1-AP (PPP1R3C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29424-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon cancer tissue using PPP1R3C Polyclonal antibody (29424-1-AP)

    IHC staining of human colon cancer using 29424-1-AP (same clone as 29424-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 29424-1-AP (PPP1R3C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29424-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon cancer tissue using PPP1R3C Polyclonal antibody (29424-1-AP)

    IHC staining of human colon cancer using 29424-1-AP (same clone as 29424-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 29424-1-AP (PPP1R3C antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29424-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29424-1-PBS bindet in WB, IHC, Indirect ELISA PPP1R3C und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PPP1R3C fusion protein Ag30280
Vollständiger Name protein phosphatase 1, regulatory (inhibitor) subunit 3C
Berechnetes Molekulargewicht 317 aa, 36 kDa
Beobachtetes Molekulargewicht36 kDa
GenBank-ZugangsnummerBC012625
Gene symbol PPP1R3C
Gene ID (NCBI) 5507
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

• Protein phosphatase 1 regulatory subunit 3C (PPP1R3C) is an enzyme that binds to protein phosphatase-1 (PP1) as a regulator. The central role of PPP1R3C is associated with glycogenesis and the overexpression of this gene increases glycogen storage. The cellular glycogen level is suppressed when PPP1R3C is knocked-down. PPP1R3C induces glycogen accumulation via HIF1 α during hypoxia and it is hypermethylated in melanoma (PMID: 25846879). Overexpression of PPP1R3C increased hepatic gluconeogenesis in vitro and in vivo while knockdown of PPP1R3C showed an opposite result (PMID: 31181215).