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PPP2CA Rekombinanter Antikörper

PPP2CA Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241112A6

Kat-Nr. : 84155-2-PBS

Synonyme

241112A6, EC:3.1.3.16, PP2A alpha, PP2A-alpha, PP2Ac

Filter:
  • Western Blot (WB) analysis of HeLa cells using PPP2CA Recombinant antibody (84155-2-RR)

    WB analysis of HeLa using 84155-2-RR (same clone as 84155-2-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 84155-2-RR (PPP2CA antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84155-2-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01058-2

    Cytometric bead array standard curve of MP01058-2

    Cytometric bead array standard curve of MP01058-2, PPP2CA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84155-2-PBS. Detection antibody: 84155-4-PBS. Standard: Ag4294. Range: 0.781-100 ng/mL.

  • Affinity and Kinetic Characterization of 84155-2-RR

    Affinity and Kinetic Characterization of 84155-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84155-2-RR against Human PPP2CA were performed. The affinity constant is 11.6 nM.

Geprüfte Anwendungen

Produktinformation

84155-2-PBS bindet in WB, Cytometric bead array, Indirect ELISA PPP2CA und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PPP2CA fusion protein Ag4294
Vollständiger Name protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Berechnetes Molekulargewicht 309 aa, 36 kDa
Beobachtetes Molekulargewicht 36 kDa
GenBank-ZugangsnummerBC031696
Gene symbol PPP2CA
Gene ID (NCBI) 5515
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.