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PPP3CA-specific Polyklonaler Antikörper

PPP3CA-specific Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55147-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using PPP3CA-specific Polyclonal antibody (55147-1-AP)

    WB analysis of mouse brain using 55147-1-AP (same clone as 55147-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 55147-1-AP (PPP3CA-specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55147-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse pancreas tissue using PPP3CA-specific Polyclonal antibody (55147-1-AP)

    WB analysis of mouse pancreas using 55147-1-AP (same clone as 55147-1-PBS)

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 55147-1-AP (PPP3CA-specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55147-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55147-1-PBS bindet in WB, Indirect ELISA PPP3CA-specific und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform
Berechnetes Molekulargewicht 59 kDa
Beobachtetes Molekulargewicht 59 kDa
GenBank-ZugangsnummerNM_000944
Gene symbol PPP3CA
Gene ID (NCBI) 5530
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PPP3CA, also called calcineurin Aα, is the only serine/threonine protein phosphatase under the control of Ca2+/calmodulin, and plays a critical role in the coupling of Ca2+ signals to cellular responses. Ca2+ signaling plays a central role in hypertrophic growth of cardiac and skeletal muscle in response to mechanical load and a variety of signals. Therefore, PPP3CA plays an important role in muscle differentiation, especially in muscle fiber type conversion. It is also involved in osteoclast regulation, regulating bone formation through an effect on osteoblast differentiation. This antibody is specific to PPP3CA.