Progesterone Receptor Monoklonaler Antikörper

Progesterone Receptor Monoklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

CloneNo.

3D1D12

Kat-Nr. : 66300-1-PBS

Synonyme

PGR, 3D1D12, NR3C3, PR, PRGR

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  IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:9900 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:9900 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:10000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66300-1-PBS bindet in IHC, ELISA Progesterone Receptor und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Progesterone Receptor fusion protein Ag22992
• Vollständiger Name: progesterone receptor
• Berechnetes Molekulargewicht: 933 aa, 99 kDa
• GenBank-Zugangsnummer: NM_000926
• Gene symbol: Progesterone Receptor
• Gene ID (NCBI): 5241
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PGR (Progesterone Receptor), also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.