PRMT7 Polyklonaler Antikörper

PRMT7 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21688-1-PBS

Synonyme

Protein arginine N-methyltransferase 7, PRMT 7, Histone-arginine N-methyltransferase PRMT7, EC:2.1.1.321, [Myelin basic protein]-arginine N-methyltransferase PRMT7

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  WB analysis using 21688-1-AP (same clone as 21688-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 21688-1-AP (PRMT7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

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  WB analysis using 21688-1-AP (same clone as 21688-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21688-1-AP (PRMT7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 21688-1-AP (same clone as 21688-1-PBS)

  IP result of anti-PRMT7 (IP:21688-1-AP, 4ug; Detection:21688-1-AP 1:1000) with HeLa cells lysate 1400 ug. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

21688-1-PBS bindet in WB, IP, Indirect ELISA PRMT7 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PRMT7 fusion protein Ag16269
• Vollständiger Name: protein arginine methyltransferase 7
• Berechnetes Molekulargewicht: 78 kDa
• Beobachtetes Molekulargewicht: 73-78 kDa
• GenBank-Zugangsnummer: BC000146
• Gene symbol: PRMT7
• Gene ID (NCBI): 54496
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protein arginine methyltransferases (PRMTs) are responsible for arginine methylation of histone or nonhistone proteins to regulate diverse biological processes, including cell proliferation, differentiation and senescence. PRMT7 is expressed in both embryonic stem and germ cells and is implicated in maintenance of muscle stem cell function. overexpression of PRMT7 has been associated with cancer metastasis. PRMT7 automethylation at residue R531 was reported to enhance breast cancer metastasis.