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PRODH Monoklonaler Antikörper

PRODH Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Kaninchen, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C3G5

Kat-Nr. : 68621-1-PBS

Synonyme

2C3G5, EC:1.5.5.2, HSPOX2, p53-induced gene 6 protein, PIG6

Filter:
  • Western Blot (WB) analysis of various lysates using PRODH Monoclonal antibody (68621-1-Ig)

    WB analysis using 68621-1-Ig (same clone as 68621-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68621-1-Ig (PRODH antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68621-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68621-1-PBS bindet in WB, Indirect ELISA PRODH und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Kaninchen, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen PRODH fusion protein Ag18429
Vollständiger Name proline dehydrogenase (oxidase) 1
Berechnetes Molekulargewicht 600 aa, 68 kDa
Beobachtetes Molekulargewicht56 kDa, 66 kDa
GenBank-ZugangsnummerBC118597
Gene symbol PRODH
Gene ID (NCBI) 5625
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PRODH(Proline dehydrogenase 1, mitochondrial) is also named as PIG6, HSPOX2, PRODH1, PRODH2, POX, SCZD4, TP53I6 and belongs to the proline oxidase family. It is an oxidoreductase involved in the transfer of redox potential across the mitochondrial membrane and catalyzes the rate-limiting oxidation of proline to pyrroline- 5-carboxylate (P5C). High PRODH activity is sufficient to induce mitochondria-mediated apoptosis in the presence of proline. Defects in PRODH are the cause of hyperprolinemia type 1 (HP-1) and defects in PRODH are associated with susceptibility to schizophrenia type 4 (SCZD4). This protein has 3 isoforms produced by alternative splicing with the molecular mass of 68 kDa, 59 kDa and 56 kDa.