PRPH2 Monoklonaler Antikörper

PRPH2 Monoklonal Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Kaninchen, Maus, Ratte

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2F11A1

Kat-Nr. : 68780-1-PBS

Synonyme

2F11A1, AOFMD, AVMD, Peripherin 2, Peripherin2

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  WB analysis using 68780-1-Ig (same clone as 68780-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68780-1-Ig (PRPH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68780-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68780-1-Ig (same clone as 68780-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68780-1-Ig (PRPH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68780-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP50146-1

  Cytometric bead array standard curve of MP50146-1, PRPH2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68780-1-PBS. Detection antibody: 68780-2-PBS. Standard:Ag12555. Range: 1.563-100 ng/mL.

• 

  Affinity and Kinetic Characterization of 68780-1-Ig

  Biolayer interferometry (BLl) kinetic assay of 68780-1-Ig against Human PRPH2 was performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

68780-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA PRPH2 und zeigt Reaktivität mit human, Kaninchen, Maus, Ratten

• Getestete Reaktivität: human, Kaninchen, Maus, Ratte
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PRPH2 fusion protein Ag12555
• Vollständiger Name: peripherin 2 (retinal degeneration, slow)
• Berechnetes Molekulargewicht: 346 aa, 39 kDa
• Beobachtetes Molekulargewicht: 35-39 kDa
• GenBank-Zugangsnummer: BC074720
• Gene symbol: PRPH2
• Gene ID (NCBI): 5961
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).