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PRR11 Polyklonaler Antikörper

PRR11 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27422-1-PBS

Synonyme

Proline rich protein 11, proline rich 11

Filter:
  • Western Blot (WB) analysis of various lysates using PRR11 Polyclonal antibody (27422-1-AP)

    WB analysis using 27422-1-AP (same clone as 27422-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27422-1-AP (PRR11 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27422-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27422-1-PBS bindet in WB, Indirect ELISA PRR11 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PRR11 fusion protein Ag26636
Vollständiger Name proline rich 11
Berechnetes Molekulargewicht 360 aa, 40 kDa
Beobachtetes Molekulargewicht38 kDa
GenBank-ZugangsnummerBC008669
Gene symbol PRR11
Gene ID (NCBI) 55771
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PRR11, or Proline-rich protein 11, is a protein-coding gene situated on chromosome 17q22-23, which plays a significant role in various cellular processes. The protein itself is composed of a nuclear localization signal (NLS), two proline-rich regions (PRs), and a zinc finger domain (ZFD) (PMID: 36551227). PRR11 has been implicated in the regulation of cell cycle, and it is involved in multiple aspects of cancer biology, including proliferation, migration, invasion, cell-cycle progression, apoptosis, autophagy, and chemotherapy resistance. It serves as a prognostic indicator in certain human cancers and is considered a potential target for therapeutic interventions (PMID: 36739300).