PSIP1 Monoklonaler Antikörper

PSIP1 Monoklonal Antikörper für Cytometric bead array, Sandwich ELISA, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Sandwich ELISA, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C4G5

Kat-Nr. : 68941-1-PBS

Synonyme

CLL associated antigen KW 7, CLL-associated antigen KW-7, DFS70, LEDGF, Lens epithelium-derived growth factor

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  Sandwich ELISA sample test of MP50375-1

  The mean PSIP1 concentration was determined to be 89.0 ng/mL in HeLa cell extract based on a 1.1 mg/mL extract load, 25.7 ng/mL in HepG2 cell extract based on a 1.2 mg/mL extract load, 99.2 ng/mL in Jurkat cell extract based on a 1.2 mg/mL extract load and 26.7 ng/mL in MCF-7 cell extract based on a 1.2 mg/mL extract load.

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  Sandwich ELISA standard curve of MP50375-1

  Sandwich ELISA standard curve of MP50375-1, Human PSIP1 Monoclonal Matched Antibody Pair - PBS only. 67723-1-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Ag21886. 68941-1-PBS was HRP conjugated as the detection antibody. Range: 93.4-6000 pg/mL.

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  Cytometric bead array standard curve of MP50375-1

  Cytometric bead array standard curve of MP50375-1, PSIP1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67723-1-PBS. Detection antibody: 68941-1-PBS. Standard:Ag21886. Range: 3.125-200 ng/mL.

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Geprüfte Anwendungen

Produktinformation

68941-1-PBS bindet in Cytometric bead array, Sandwich ELISA, Indirect ELISA PSIP1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PSIP1 fusion protein Ag21886
• Vollständiger Name: PC4 and SFRS1 interacting protein 1
• Berechnetes Molekulargewicht: 530 aa, 60 kDa
• GenBank-Zugangsnummer: BC064135
• Gene symbol: PSIP1
• Gene ID (NCBI): 11168
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PSIP1, also known as PC4 and SRSF1 Interacting Protein 1 or Lens Epithelium-Derived Growth Factor (LEDGF), is a transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. It also plays a role in lens epithelial cell gene regulation and stress responses. It is a chromatin-associated protein with histone chaperone activity, involved in transcriptional elongation. PSIP1 may act as an adapter to coordinate pre-mRNA splicing. PSIP1 encodes two protein isoforms with molecular masses of 52 and 75 kDa. p52 and p75 were identified as interacting with transcription factor PC4 and shown to act as transcriptional coactivators.