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PSMA/GCPII Rekombinanter Antikörper

PSMA/GCPII Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242026E6

Kat-Nr. : 98279-1-PBS

Synonyme

FOLH1, PSMA, 242026E6, Cell growth-inhibiting gene 27 protein, EC:3.4.17.21

Filter:
  • Flow cytometry (FC) experiment of LNCaP cells using Anti-Human PSMA/GCPII Rabbit Recombinant Antibody (98279-1-RR)

    FC experiment of LNCaP using 98279-1-RR (same clone as 98279-1-PBS)

    1x10^6 LNCaP cells (left) or HeLa (right) were surface stained with 0.25 ug Anti-Human FOLH1 Rabbit RecAb (98279-1-RR, Clone: 242026E6) (red),or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue)and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98279-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98279-1-RR

    Affinity and Kinetic Characterization of 98279-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98279-1-RR against Human PSMA/GCPII were performed. The affinity constant is 49.6 nM.

Geprüfte Anwendungen

Produktinformation

98279-1-PBS bindet in FC PSMA/GCPII und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name folate hydrolase (prostate-specific membrane antigen) 1
Berechnetes Molekulargewicht84KD
GenBank-ZugangsnummerNM_004476.3
Gene symbol PSMA
Gene ID (NCBI) 2346
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

PSMA (Prostate-specific membrane antigen) is also named as FOLH1, FOLH, NAALAD1, PSM and belongs to the peptidase M28 family. PSMA is a 100-120 kDa integral transmembrane glycoprotein, considered to be a highly specific marker of the prostate gland, and has successfully been used as a marker of circulating prostatic epithelial cells(PMID:10074909; 15680901). It is involved in conversion of the major neurotransmitter (NAAG) to NAA and free glutamate. It has 8 isoforms produced by alternative splicing.