PSMA/GCPII Rekombinanter Antikörper

PSMA/GCPII Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242026E6

Kat-Nr. : 98279-1-RR

Synonyme

FOLH1, PSMA, 242026E6, Cell growth-inhibiting gene 27 protein, EC:3.4.17.21

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  FC experiment of LNCaP using 98279-1-RR

  1x10^6 LNCaP cells (left) or HeLa (right) were surface stained with 0.25 ug Anti-Human FOLH1 Rabbit RecAb (98279-1-RR, Clone: 242026E6) (red),or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue)and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98279-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98279-1-RR against Human PSMA/GCPII were performed. The affinity constant is 49.6 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: LNCaP-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98279-1-RR bindet in FC PSMA/GCPII und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: folate hydrolase (prostate-specific membrane antigen) 1
• Berechnetes Molekulargewicht: 84KD
• GenBank-Zugangsnummer: NM_004476.3
• Gene symbol: PSMA
• Gene ID (NCBI): 2346
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

PSMA (Prostate-specific membrane antigen) is also named as FOLH1, FOLH, NAALAD1, PSM and belongs to the peptidase M28 family. PSMA is a 100-120 kDa integral transmembrane glycoprotein, considered to be a highly specific marker of the prostate gland, and has successfully been used as a marker of circulating prostatic epithelial cells(PMID:10074909; 15680901). It is involved in conversion of the major neurotransmitter (NAAG) to NAA and free glutamate. It has 8 isoforms produced by alternative splicing.