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PSMB10 Polyklonaler Antikörper

PSMB10 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15976-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using PSMB10 Polyclonal antibody (15976-1-AP)

    WB analysis using 15976-1-AP (same clone as 15976-1-PBS)

    Raji cells were subjected to SDS PAGE followed by western blot with 15976-1-AP (PSMB10 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15976-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human liver tissue using PSMB10 Polyclonal antibody (15976-1-AP)

    WB analysis of human liver using 15976-1-AP (same clone as 15976-1-PBS)

    human liver tissue were subjected to SDS PAGE followed by western blot with 15976-1-AP (PSMB10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15976-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using PSMB10 Polyclonal antibody (15976-1-AP)

    IHC staining of human liver cancer using 15976-1-AP (same clone as 15976-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 15976-1-AP (PSMB10 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15976-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using PSMB10 Polyclonal antibody (15976-1-AP)

    IHC staining of human liver cancer using 15976-1-AP (same clone as 15976-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 15976-1-AP (PSMB10 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15976-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

15976-1-PBS bindet in WB, IHC, Indirect ELISA PSMB10 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PSMB10 fusion protein Ag8764
Vollständiger Name proteasome (prosome, macropain) subunit, beta type, 10
Berechnetes Molekulargewicht 273 aa, 29 kDa
Beobachtetes Molekulargewicht 29 kDa
GenBank-ZugangsnummerBC017198
Gene symbol PSMB10
Gene ID (NCBI) 5699
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The proteasome subunit, beta type 10 (PSMB10) gene regulated by interferon-gamma is a core part of the 26S proteasome complex, which is an important protein degrading system. Study identifies immunosubunit PSMB10 as a novel regulator that contributes to Ang II-induced atrial fibrillation (AF) and suggests that inhibition of PSMB10 may represent a potential therapeutic target for treating hypertensive AF. (PMID: 29507100, PMID: 16965406)