PSMB7 Monoklonaler Antikörper

PSMB7 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3D7B8

Kat-Nr. : 68641-1-PBS

Synonyme

Z, Proteasome subunit beta type-7, EC:3.4.25.1, 3D7B8

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  WB analysis using 68641-1-Ig (same clone as 68641-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68641-1-Ig (PSMB7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 68641-1-Ig (same clone as 68641-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 68641-1-Ig (PSMB7 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 68641-1-Ig (same clone as 68641-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 68641-1-Ig (PSMB7 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin cancer using 68641-1-Ig (same clone as 68641-1-PBS)

  Immunohistochemical analysis of paraffin-embedded skin cancer slide using 68641-1-Ig (PSMB7 antibody) at dilution of 1:2000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68641-1-PBS bindet in WB, IHC, Indirect ELISA PSMB7 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PSMB7 fusion protein Ag6544
• Vollständiger Name: proteasome (prosome, macropain) subunit, beta type, 7
• Berechnetes Molekulargewicht: 29.9 kDa
• Beobachtetes Molekulargewicht: 28-30 kDa
• GenBank-Zugangsnummer: BC000509
• Gene symbol: PSMB7
• Gene ID (NCBI): 5695
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. PSMB7 protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. Component of the 20S core proteasome complex are involved in the proteolytic degradation of most intracellular proteins. PSMB7 displays a trypsin-like activity.(PMID:15244466, PMID:27176742, PMID: 8610016)