PSMD2 Monoklonaler Antikörper

PSMD2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1G7G5

Kat-Nr. : 67770-1-PBS

Synonyme

TRAP2, S2, Rpn1, P97, 26S proteasome non-ATPase regulatory subunit 2



Geprüfte Anwendungen

Produktinformation

67770-1-PBS bindet in WB, Indirect ELISA PSMD2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen PSMD2 fusion protein Ag6543
Vollständiger Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Berechnetes Molekulargewicht 100 kDa
Beobachtetes Molekulargewicht100 kDa
GenBank-ZugangsnummerBC002368
Gene symbol PSMD2
Gene ID (NCBI) 5708
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tumor necrosis factor type 1 receptor-associated protein 2 (TRAP2), encoded by PSMD2 gene, is a non-ATPase regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. TRAP2 may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor.