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PSMD8 Polyklonaler Antikörper

PSMD8 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27504-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using PSMD8 Polyclonal antibody (27504-1-AP)

    WB analysis using 27504-1-AP (same clone as 27504-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 27504-1-AP (PSMD8 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27504-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using PSMD8 Polyclonal antibody (27504-1-AP)

    IF Staining of U2OS using 27504-1-AP (same clone as 27504-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using PSMD8 antibody (27504-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27504-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27504-1-PBS bindet in WB, IF/ICC, Indirect ELISA PSMD8 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PSMD8 fusion protein Ag26567
Vollständiger Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Berechnetes Molekulargewicht 257 aa, 30 kDa
Beobachtetes Molekulargewicht30 kDa
GenBank-ZugangsnummerBC001164
Gene symbol PSMD8
Gene ID (NCBI) 5714
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The Proteasome 26S Subunit, Non-ATPase (PSMD) gene family, which includes the PSMD1 to PSMD14, regulate ubiqutinated protein breakdown in circulation as well as tumorigenesis. Studies have shown that PSMD8 interacts with the sperm adhesin AQN1 to limit polyfertilization. PSMD8 was more expressed in normal skeletal muscle, cardiac muscle, and tongue muscle; among malignant tumors, PSMD8 was expressed in ovarian cancer, testicular cancer, glioma, and melanoma(PMID:37349676).