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PTGER3 Polyklonaler Antikörper

PTGER3 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14357-1-PBS

Synonyme

EP3, EP3 I, EP3 II, EP3 III, EP3 IV

Filter:
  • Immunohistochemistry (IHC) staining of human brain tissue using PTGER3 Polyclonal antibody (14357-1-AP)

    IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14357-1-AP (PTGER3 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 14357-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using PTGER3 Polyclonal antibody (14357-1-AP)

    IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14357-1-AP (PTGER3 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 14357-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14357-1-PBS bindet in IHC, Indirect ELISA PTGER3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PTGER3 fusion protein Ag5711
Vollständiger Name prostaglandin E receptor 3 (subtype EP3)
Berechnetes Molekulargewicht 43 kDa
GenBank-ZugangsnummerBC024229
Gene symbol PTGER3
Gene ID (NCBI) 5733
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PTGER3 (Prostaglandin E Receptor 3), also known as EP3, is a G protein-coupled receptor (GPCR). Activates pathways involved in proliferation, migration, and apoptosis, often via cross-talk with PI3K-AKT and MAPK cascades (PMID: 38566528). High PTGER3 levels drive tumorigenesis, angiogenesis, and cisplatin resistance via the Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis (PMID: 30655206).