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PTK6/BRK Rekombinanter Antikörper

PTK6/BRK Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242647F4

Kat-Nr. : 85352-2-PBS

Synonyme

PTK6, BRK, 242647F4, Protein-tyrosine kinase 6, Protein tyrosine kinase 6

Filter:
  • Western Blot (WB) analysis of various lysates using PTK6/BRK Recombinant antibody (85352-2-RR)

    WB analysis using 85352-2-RR (same clone as 85352-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85352-2-RR (PTK6/BRK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85352-2-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A549 cells using PTK6/BRK Recombinant antibody (85352-2-RR)

    IF Staining of A549 using 85352-2-RR (same clone as 85352-2-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed A549 cells using PTK6 antibody (85352-2-RR, Clone: 242647F4 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85352-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85352-2-PBS bindet in WB, IF/ICC, Indirect ELISA PTK6/BRK und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name PTK6 protein tyrosine kinase 6
Berechnetes Molekulargewicht 52 kDa
Beobachtetes Molekulargewicht 52 kDa
GenBank-ZugangsnummerBC035843
Gene symbol PTK6
Gene ID (NCBI) 5753
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BRK, also named as PTK6 and FLJ42088, is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. PTK6 can phosphorylate KHDRBS1, KHDRBS2, KHDRBS3 and STAP2/BKS. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. This antibody is specific to PTK6.