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PTPIP51 Monoklonaler Antikörper

PTPIP51 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1G11E2

Kat-Nr. : 68582-1-PBS

Synonyme

FAM82A2, 1G11E2, FAM82C, hRMD 3, hRMD-3

Filter:
  • Western Blot (WB) analysis of various lysates using PTPIP51 Monoclonal antibody (68582-1-Ig)

    WB analysis using 68582-1-Ig (same clone as 68582-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68582-1-Ig (PTPIP51 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68582-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using PTPIP51 Monoclonal antibody (68582-1-Ig)

    IF Staining of HeLa using 68582-1-Ig (same clone as 68582-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using PTPIP51 antibody (68582-1-Ig, Clone: 1G11E2 ) at dilution of 1:476 and Multi-rAb CoraLite® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (Cat.NO. RGAM004 ). This data was developed using the same antibody clone with 68582-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68582-1-PBS bindet in WB, IF/ICC, Indirect ELISA PTPIP51 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen PTPIP51 fusion protein Ag15135
Vollständiger Name family with sequence similarity 82, member A2
Berechnetes Molekulargewicht 470 aa, 52 kDa
Beobachtetes Molekulargewicht52-60 kDa
GenBank-ZugangsnummerBC008970
Gene symbol PTPIP51
Gene ID (NCBI) 55177
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protein tyrosine phosphatase-interacting protein 51 (PTPIP51),also known as RMDN3, is a mitochondrial membrane-anchored protein that interacts with ER membrane-bound VAPB. The VAPB-PTPIP51 interaction impacts on intracellular Ca2+ handling (PMID: 22131369, 28345618). PTPIP51 participates in multiple cellular processes, and dysfunction of PTPIP51 is implicated in diseases such as cancer and neurodegenerative disorders (PMID: 28345618).The known initiation sites in the Ptpip51 gene would lead to molecular protein masses of 52, 38 and 30 kDa (PMID: 18854601,19844996).