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PTPN1/PTP1B Rekombinanter Antikörper

PTPN1/PTP1B Rekombinant Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

250215G5

Kat-Nr. : 85905-5-RR

Synonyme

PTP1B, PTPN1, EC:3.1.3.48, Protein-tyrosine phosphatase 1B, PTP 1B

Geprüfte Anwendungen

Produktinformation

85905-5-RR bindet in ELISA PTPN1/PTP1B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PTPN1/PTP1B fusion protein Ag1878
Vollständiger Name protein tyrosine phosphatase, non-receptor type 1
Berechnetes Molekulargewicht 435 aa, 50 kDa
Beobachtetes Molekulargewicht52 kDa
GenBank-ZugangsnummerBC015660
Gene symbol PTP1B
Gene ID (NCBI) 5770
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PTPN1 (protein tyrosine phosphatase, non-receptor type 1) is also named as PTP1B or PTP-1B, and belongs to the protein-tyrosine phosphatase family and non-receptor class 1 subfamily. PTPN1 is involved in the regulation of several important physiological pathways, which regulates both INS and leptin signaling, and interacts with the epidermal-and platelet-derived growth factor receptors (PMID: 20101100). The gene might harbor variants influencing susceptibility to INS resistance and type 2 diabetes (PMID:15919813). The molecular mass of PTPN1 is 50 kDa, but sometimes some truncated forms can be detected as 48, 46, 39, 37 kDa due to non-specific proteolytic cleavage of PTP1B in different cells (PMID: 18253097).