PTPN2 Monoklonaler Antikörper

PTPN2 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2A1D1

Kat-Nr. : 67388-1-PBS

Synonyme

2A1D1, EC:3.1.3.48, PTN2, PTPN 2, PTPT

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  WB analysis using 67388-1-Ig (same clone as 67388-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67388-1-Ig (PTPN2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 67388-1-Ig (same clone as 67388-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67388-1-Ig (PTPN2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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  WB analysis of 4T1 using 67388-1-Ig (same clone as 67388-1-PBS)

  4T1 cells were subjected to SDS PAGE followed by western blot with 67388-1-Ig (PTPN2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 67388-1-Ig (same clone as 67388-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67388-1-Ig (PTPN2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 67388-1-Ig (same clone as 67388-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67388-1-Ig (PTPN2 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67388-1-PBS bindet in WB, IHC, Indirect ELISA PTPN2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PTPN2 fusion protein Ag29749
• Vollständiger Name: protein tyrosine phosphatase, non-receptor type 2
• Berechnetes Molekulargewicht: 49 kDa
• Beobachtetes Molekulargewicht: 45-50 kDa
• GenBank-Zugangsnummer: BC016727
• Gene symbol: PTPN2
• Gene ID (NCBI): 5771
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PTPN2(Tyrosine-protein phosphatase non-receptor type 2) is also named as PTPT and belongs to the protein-tyrosine phosphatase family. It may modulate beta-cell apoptosis and/or local release of inflammatory mediators in the course of a viral infection by acting, at least in part, at the pancreatic beta-cell level(PMID: 19825843). This protein has some isoforms produced by alternative splicing with the molecular mass of 40-50 kDa.