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PTPRK Polyklonaler Antikörper

PTPRK Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28151-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using PTPRK Polyclonal antibody (28151-1-AP)

    WB analysis using 28151-1-AP (same clone as 28151-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28151-1-AP (PTPRK antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28151-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using PTPRK Polyclonal antibody (28151-1-AP)

    WB analysis using 28151-1-AP (same clone as 28151-1-PBS)

    mouse spleen tissue were subjected to SDS PAGE followed by western blot with 28151-1-AP (PTPRK antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28151-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28151-1-PBS bindet in WB, Indirect ELISA PTPRK und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen PTPRK fusion protein Ag27765
Vollständiger Name protein tyrosine phosphatase, receptor type, K
Berechnetes Molekulargewicht 1439 aa, 162 kDa
Beobachtetes Molekulargewicht 100-120 kDa
GenBank-ZugangsnummerBC140775
Gene symbol PTPRK
Gene ID (NCBI) 5796
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PTPRK (Protein Tyrosine Phosphatase Receptor Type Kappa), a member of the receptor-type protein tyrosine phosphatase family, is a transmembrane protein that regulates cell-cell contact. PTPRK is a 210 kDa precursor protein and converted by furin to a mature heterodimeric protein composed of a non-covalently attached amino-terminal extracellular subunit (E-subunit, 120 kDa) and carboxyl-terminal transmembrane subunit (P-subunit, 95 kDa) (PMID: 24882578, 16648485). Loss of PTPRK activity has been observed in pancreatic cancer, primary CNS lymphoma and melanoma, and is associated with poor survival of cancer patients, which suggest that PTPRK is a potential tumor suppressor (PMID: 23696788).