PTPRR Polyklonaler Antikörper

PTPRR Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17937-1-PBS

Synonyme

Ch-1PTPase, EC PTP, EC:3.1.3.48, ECPTP, NC-PTPCOM1

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  WB analysis using 17937-1-AP (same clone as 17937-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 17937-1-AP (same clone as 17937-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

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  WB analysis of COLO 320 using 17937-1-AP (same clone as 17937-1-PBS)

  COLO 320 cells were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 17937-1-AP (same clone as 17937-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

17937-1-PBS bindet in WB, ELISA PTPRR und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PTPRR fusion protein Ag12145
• Vollständiger Name: protein tyrosine phosphatase, receptor type, R
• Berechnetes Molekulargewicht: 657 aa, 74 kDa
• Beobachtetes Molekulargewicht: 32 kDa, 47 kDa, 65 kDa
• GenBank-Zugangsnummer: BC110900
• Gene symbol: PTPRR
• Gene ID (NCBI): 5801
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PTPRR(protein tyrosine phosphatase, receptor type, R) is also named as PCPTP1, PTP-SL, PTPBR7 and belongs to the protein-tyrosine phosphatase family. It sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. It has four isoforms that they have molecular weights of 72, 60, 42 and 37 kDa, respectively, and differ in the length of their N-terminal part which result in distinct subcellular localizations. All PTPRR isoforms are found to be short-lived proteins, with half-lives of around 3-5 hours, and are constitutively phosphorylated on one or two of the previously identified protein kinase A and MAP kinase target sites.