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PTPRS Polyklonaler Antikörper

PTPRS Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31720-1-PBS

Synonyme

Receptor-type tyrosine-protein phosphatase sigma, Receptor-type tyrosine-protein phosphatase S, R PTP sigma, R PTP S, PTPSIGMA

Filter:
  • Western Blot (WB) analysis of various lysates using PTPRS Polyclonal antibody (31720-1-AP)

    WB analysis using 31720-1-AP (same clone as 31720-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31720-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using PTPRS Polyclonal antibody (31720-1-AP)

    WB analysis using 31720-1-AP (same clone as 31720-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31720-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31720-1-PBS bindet in WB, Indirect ELISA PTPRS und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name protein tyrosine phosphatase, receptor type, S
Berechnetes Molekulargewicht217 kDa
Beobachtetes Molekulargewicht140 kDa
GenBank-ZugangsnummerNM_002850
Gene symbol PTPRS
Gene ID (NCBI) 5802
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protein tyrosine phosphatase receptor type S (PTPRS, also known as R-PTP-S, PTPSIGMA, and R-PTP-sigma) is an integral membrane protein. It can promote oligomerization by binding to large heparan sulfate proteoglycan structures, and interact with NTRK1/3, PPFIA1/2/3 (PMID: 25385546; 8524829; 9624153). The non-glycosylated molecular weight of PTPRS is 214 kDa, and the extracellular domain can be cleaved near the cell membrane by an endoprotease to generate a glycated 140 kDa protein. Variations and mutations of PTPRS are associated with Alzheimer's disease and cholangiocarcinoma (PMID: 38766183; 35991009).