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PYGB Rekombinanter Antikörper

PYGB Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251450C3

Kat-Nr. : 86737-3-PBS

Synonyme

EC:2.4.1.1, GPBB, phosphorylase, glycogen; brain

Filter:
  • Western Blot (WB) analysis of various lysates using PYGB Recombinant monoclonal antibody (86737-3-RR)

    WB analysis using 86737-3-RR (same clone as 86737-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86737-3-RR (PYGB antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86737-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86737-3-RR

    Affinity and Kinetic Characterization of 86737-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86737-3-RR against Human PYGB were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

86737-3-PBS bindet in WB, Indirect ELISA PYGB und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen PYGB fusion protein Ag2732
Vollständiger Name phosphorylase, glycogen; brain
Berechnetes Molekulargewicht 843 aa, 97 kDa
Beobachtetes Molekulargewicht97 kDa
GenBank-ZugangsnummerBC017045
Gene symbol PYGB
Gene ID (NCBI) 5834
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The three main subtypes of GP found in human tissues-brain-type glycogen phosphorylase (PYGB), liver-type glycogen phosphorylase (PYGL), and muscle-type glycogen phosphorylase (PYGM)-differ in function, structure, and tissue distribution. PYGB (Brain‑type glycogen phosphorylase) is a glycogen phosphorylase and is primarily localized in adult brain tissues and embryo liver tissues, whose function is to provide energy to organisms (PMID: 30106110). PYGB has been observed to be overexpressed in many types of cancer and tumor cell lines and is expected to be a novel target for the diagnosis and treatment of various cancers (PMID: 38334681).