PYROXD2 Polyklonaler Antikörper

PYROXD2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21845-1-PBS

Synonyme

C10orf33, FP3420, YueF

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  WB analysis using 21845-1-AP (same clone as 21845-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21845-1-AP (PYROXD2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21845-1-PBS in a different storage buffer formulation.

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  IHC staining of rat liver using 21845-1-AP (same clone as 21845-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 21845-1-AP (PYROXD2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21845-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 21845-1-AP (same clone as 21845-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 21845-1-AP (PYROXD2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21845-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 21845-1-AP (same clone as 21845-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 21845-1-AP (PYROXD2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21845-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 21845-1-AP (same clone as 21845-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 21845-1-AP (PYROXD2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21845-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

21845-1-PBS bindet in WB, IHC, Indirect ELISA PYROXD2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PYROXD2 fusion protein Ag15004
• Vollständiger Name: chromosome 10 open reading frame 33
• Berechnetes Molekulargewicht: 581 aa, 63 kDa
• Beobachtetes Molekulargewicht: 63 kDa
• GenBank-Zugangsnummer: BC006131
• Gene symbol: PYROXD2
• Gene ID (NCBI): 84795
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Pyridine Nucleotide-Disulfide Oxidoreductase Domain 2 (PYROXD2, previously called YueF, C10orf33) is a mitochondrial inner membrane/matrix-residing protein and is reported to regulate mitochondrial function. PYROXD2 is highly expressed in the cytoplasm of normal cells and tissues but is expressed at lower levels in corresponding cancer cells, including liver, lung and renal cell carcinoma and bladder cancer cells (PMID: 29048625, PMID: 35606887).