Pannexin 3 Polyklonaler Antikörper

Pannexin 3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31736-1-PBS

Synonyme

PANX3, PX3

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  WB analysis using 31736-1-AP (same clone as 31736-1-PBS)

  U2OS cells were subjected to SDS PAGE followed by western blot with 31736-1-AP (Pannexin 3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31736-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

31736-1-PBS bindet in WB, Indirect ELISA Pannexin 3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Pannexin 3 fusion protein Ag34451
• Vollständiger Name: pannexin 3
• Berechnetes Molekulargewicht: 392 aa, 45 kDa
• Beobachtetes Molekulargewicht: 43 kDa
• GenBank-Zugangsnummer: NM_052959
• Gene symbol: PANX3
• Gene ID (NCBI): 116337
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Pannexin 3 (PANX3) is a member of the pannexin family of single membrane channel-forming glycoproteins. PANX3 is expressed in osteoblasts, chondrocytes, and skin and plays a major role in calcium homeostasis suggesting an independent functional niche. PANX3 regulates both chondrocyte and osteoblast differentiation via the activation of intracellular Ca2+ signaling pathways through multiple channel activities: hemichannels, endoplasmic reticulum (ER) Ca2+ channels, and gap junctions. PANX3 has 392 amino acids with a molecular weight of ~ 43 kDa and is N-linked glycosylated at asparagine residue 71 in the first extracellular loop (PMID: 27837015, PMID: 34250568, PMID: 38580658).