Periostin Polyklonaler Antikörper

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Periostin Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19899-1-PBS

Synonyme

OSF 2, OSF2, OSF-2, Osteoblast specific factor 2, Osteoblast-specific factor 2

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  IHC staining of human skin cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 19899-1-AP (Periostin antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 19899-1-AP (Periostin antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

19899-1-PBS bindet in IHC, Indirect ELISA Periostin und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Periostin fusion protein Ag13791
• Vollständiger Name: periostin, osteoblast specific factor
• Berechnetes Molekulargewicht: 93 kDa
• GenBank-Zugangsnummer: BC106710
• Gene symbol: Periostin
• Gene ID (NCBI): 10631
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Periostin (POSTN, PN), originally named as osteoblast-specific factor 2 (OSF-2), is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues, and has a role in bone, tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types, including lung, ovary, breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour, and it is required to allow cancer stem cell maintenance. The isoforms of periostin are between 83 and 93 kDa in mass and differ in their C-terminal sequences, characterized by individual presence or absence of cassette exons 17-21 (UniProtKB/Swiss-Prot,PMID: 21997759).