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Phospho-CrkL (Tyr207) Rekombinanter Antikörper

Phospho-CrkL (Tyr207) Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240881A2

Kat-Nr. : 84590-2-PBS

Synonyme

CrkL (Tyr207), p CrkL, p CrkL (Tyr207), p-CrkL, p-CrkL (Tyr207)

Filter:
  • Western Blot (WB) analysis of NIH/3T3 cells using Phospho-CrkL (Tyr207) Recombinant antibody (84590-2-RR)

    WB analysis of NIH/3T3 using 84590-2-RR (same clone as 84590-2-PBS)

    Non-treated NIH/3T3 cells and Blocked Phosphorylated peptide treated NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 84590-2-RR (Phospho-CrkL (Tyr207) antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. The membrane was stripped and re-blotted with Alpha Tubulin (66031-1-Ig) antibody as a loading control. This data was developed using the same antibody clone with 84590-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84590-2-PBS bindet in WB, Indirect ELISA Phospho-CrkL (Tyr207) und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name v-crk sarcoma virus CT10 oncogene homolog (avian)-like
Berechnetes Molekulargewicht 34 kDa
GenBank-ZugangsnummerBC043500
Gene symbol CRKL
Gene ID (NCBI) 1399
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CrkL (v-crk avian sarcoma virus CT10 oncogene homolog-like) is a cytoplasmic adaptor protein that belongs to the Crk family of adaptors. Similar to other adaptor proteins, Crk functions primarily to assemble molecular complexes to distribute signals within the cell. The best studied regulatory mechanism of Crk proteins is the phosphorylation at a tyrosine located in a linker between the N- and C-terminal SH3 domains (Tyr221 in human CrkII, Tyr207 in human CrkL). (PMID: 24675776)