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Phospho-MNK1 (Thr250/255) Rekombinanter Antikörper

Phospho-MNK1 (Thr250/255) Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4P9

Kat-Nr. : 81398-1-PBS

Synonyme

MKNK1, Mnk1, MAPK signal-integrating kinase 1, MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1



Geprüfte Anwendungen

Produktinformation

81398-1-PBS bindet in WB, Indirect ELISA Phospho-MNK1 (Thr250/255) und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name MAP kinase interacting serine/threonine kinase 1
Berechnetes Molekulargewicht 51 kDa
Beobachtetes Molekulargewicht51 kDa
GenBank-ZugangsnummerBC002755
Gene symbol MNK1
Gene ID (NCBI) 8569
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MNK1/MKNK1 (MAPK Interacting Serine/Threonine Kinase 1) is a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. MNK1 regulates diverse biologic processes including translation, cell proliferation, and differentiation through phosphorylation of different substrates(PMID: 29045529). Through phosphorylation MNK1 regulates the function of eukaryotic translation initiation factor 4E (eIF4E), a key player in translational control, whose expression is mostly upregulated in cancer patients.