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Phospho-MNK1 (Thr250/255) Rekombinanter Antikörper
Phospho-MNK1 (Thr250/255) Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
4P9
Kat-Nr. : 81398-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
81398-1-PBS bindet in WB, Indirect ELISA Phospho-MNK1 (Thr250/255) und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Peptid |
Vollständiger Name | MAP kinase interacting serine/threonine kinase 1 |
Berechnetes Molekulargewicht | 51 kDa |
Beobachtetes Molekulargewicht | 51 kDa |
GenBank-Zugangsnummer | BC002755 |
Gene symbol | MNK1 |
Gene ID (NCBI) | 8569 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
MNK1/MKNK1 (MAPK Interacting Serine/Threonine Kinase 1) is a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. MNK1 regulates diverse biologic processes including translation, cell proliferation, and differentiation through phosphorylation of different substrates(PMID: 29045529). Through phosphorylation MNK1 regulates the function of eukaryotic translation initiation factor 4E (eIF4E), a key player in translational control, whose expression is mostly upregulated in cancer patients.