Phospho-PKC Delta (Thr507) Polyklonaler Antikörper
Phospho-PKC Delta (Thr507) Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 29564-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
29564-1-PBS bindet in WB, Indirect ELISA Phospho-PKC Delta (Thr507) und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Polyklonal |
Typ | Antikörper |
Immunogen | Peptid |
Vollständiger Name | protein kinase C, delta |
Berechnetes Molekulargewicht | 78 kDa |
Beobachtetes Molekulargewicht | 70 kDa |
GenBank-Zugangsnummer | BC043350 |
Gene symbol | PKC Delta |
Gene ID (NCBI) | 5580 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Antigen-Affinitätsreinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
PKC Delta(PRKCD) is a member of the PKC family, a phospholipid-dependent family of serine/threonine kinases, and is present in human neutrophils. Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine. Three specific sites; Thr-507 (activation loop of the kinase domain), Ser-645 (turn motif) and Ser-664 (hydrophobic region), need to be phosphorylated for its full activation. This antibody is equivalent to Thr505 in mice.