Phospho-RIPK1 (Ser161) Monoklonaler Antikörper
Phospho-RIPK1 (Ser161) Monoklonal Antikörper für WB, IHC, IF/ICC, FC (Intra), ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
WB, IHC, IF/ICC, FC (Intra), ELISA
Konjugation
Unkonjugiert
CloneNo.
1B2G1
Kat-Nr. : 66854-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66854-1-PBS bindet in WB, IHC, IF/ICC, FC (Intra), ELISA Phospho-RIPK1 (Ser161) und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Peptid |
Vollständiger Name | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
Berechnetes Molekulargewicht | 76 kDa |
Beobachtetes Molekulargewicht | 74 kDa, 45 kDa |
GenBank-Zugangsnummer | NM_003804 |
Gene symbol | RIPK1 |
Gene ID (NCBI) | 8737 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis and necroptosis and belongs to a novel class of kinases thatfunction in cell survival and cell death mechanisms(PMID:22685397 ).It has 2 isoforms produced by alternative splicing.It also can exist as the protein with lower molecular weight about 25kd and 45kd in HAEC and HUVEC(PMID:22685397).