Phospho-TAU (Ser202/Thr205) Rekombinanter Antikörper

Phospho-TAU (Ser202/Thr205) Rekombinant Antikörper für WB, IF-P, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF-P, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

CloneNo.

4A6

Kat-Nr. : 82568-1-RR

Synonyme

p TAU, p TAU (Ser202/Thr205), p TAU Ser202/Thr205, Phospho TAU, Phospho TAU (Ser202/Thr205)



Geprüfte Anwendungen

Erfolgreiche Detektion in WBMaushirngewebe
Erfolgreiche Detektion in IF-PMaushirngewebe

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:5000-1:50000
Immunfluoreszenz (IF)-PIF-P : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

WBSee 3 publications below

Produktinformation

82568-1-RR bindet in WB, IF-P, ELISA Phospho-TAU (Ser202/Thr205) und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
In Publikationen genannte ReaktivitätMaus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name microtubule-associated protein tau
Berechnetes Molekulargewicht 37-46, 79-81 kDa
Beobachtetes Molekulargewicht45-55 kDa
GenBank-ZugangsnummerBC000558
Gene symbol TAU
Gene ID (NCBI) 4137
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tau (tubulin-associated unit) is a microtubule-associated protein (also known as MAPT), expressed mainly in neurons of the central nervous system. Its primary function is to modulate microtubule dynamics for maintaining axonal cytoskeleton. The Tau protein has six isoforms produced from a single gene through alternative RNA splicing. Isoforms differ in number of inserts at the N-terminal half and the number of repeats at the C-terminal half (3 repeat-3R; 4 repeat-4R). Tau is hyperphosphorylated during aging and in age-related neurodegenerative diseases such as Alzheimer's disease (AD) and fronto-temporal dementia. Hyperphosphorylation of Tau leads to the formation of neurofibrillary tangles (NFT) in the neurons and glia cells, which is one of the hallmarks of AD.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for Phospho-TAU (Ser202/Thr205) antibody 82568-1-RRProtokoll herunterladen
IF protocol for Phospho-TAU (Ser202/Thr205) antibody 82568-1-RRProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseWB

Foods

Comparative Analysis of Egg Yolk Phospholipid Unsaturation and Its Impact on Neural Health in Alzheimer Disease Mice

Authors - Yuhang Sun
mouseWB

Open Life Sci

Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease

Authors - Shiguo Lin
mouseWB

Exp Clin Endocrinol Diabetes

Beneficial effects of Echinacoside on cognitive impairment and diabetes in type 2 diabetic db/db mice

Authors - Fanglin Qin

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Camille (Verified Customer) (02-17-2025)

We used the antibody 82568-1-RR for an IHC on human samples and it worked nicely at a dilution of 1/1000

  • Applications: Immunohistochemistry
  • Primary Antibody Dilution: 1/1000
FH

Marion (Verified Customer) (11-21-2024)

This antibody was tested to reveal Tau phosporylation in a murine AD model. We are satisfied with the results.

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1/400
  • Cell Tissue Type: Mouse Brain
Phospho-TAU (Ser202/Thr205) Antibody Immunofluorescence validation (1/400 dilution) in Mouse Brain (Cat no:82568-1-RR)