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Phospho-TAU (Thr205) Rekombinanter Antikörper

Phospho-TAU (Thr205) Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251173E12

Kat-Nr. : 86669-1-PBS

Synonyme

MAPT, TAU, AT180, DDPAC, MAPTL

Filter:
  • Western Blot (WB) analysis of various lysates using Phospho-TAU (Thr205) Recombinant monoclonal antibo (86669-1-RR)

    WB analysis using 86669-1-RR (same clone as 86669-1-PBS)

    Phosphatase inhibitor treated and λ phosphatase treated mouse brain tissue were subjected to SDS PAGE followed by western blot with 86669-1-RR (Phospho-TAU (Thr205) antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and re-blotted with GAPDH antibody (60004-1-Ig) as loading control. This data was developed using the same antibody clone with 86669-1-PBS in a different storage buffer formulation.

  • WB analysis using 86669-1-RR

    WB analysis using 86669-1-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 86669-1-RR (Phospho-TAU (Thr205) antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Produktinformation

86669-1-PBS bindet in WB, Indirect ELISA Phospho-TAU (Thr205) und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name microtubule-associated protein tau
Berechnetes Molekulargewicht 37-46, 79-81 kDa
Beobachtetes Molekulargewicht45-60 kDa
GenBank-ZugangsnummerBC000558
Gene symbol TAU
Gene ID (NCBI) 4137
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tau is hyperphosphorylated during aging and in age-related neurodegenerative diseases such as Alzheimer's disease (AD) and fronto-temporal dementia. Hyperphosphorylation of Tau leads to the formation of neurofibrillary tangles (NFT) in the neurons and glia cells, which is one of the hallmarks of AD.