Prion protein PrP/CD230 Rekombinanter Antikörper

Prion protein PrP/CD230 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

243104D11

Kat-Nr. : 98414-4-PBS

Synonyme

Prion protein PrP, PRNP, PrP, Alternative prion protein, AltPrP

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  FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98414-4-PBS bindet in FC Prion protein PrP/CD230 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Prion protein PrP/CD230 fusion protein Eg3359
• Vollständiger Name: prion protein
• GenBank-Zugangsnummer: BC012844
• Gene symbol: PrP
• Gene ID (NCBI): 5621
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

The major prion protein (PrP), also known as CD230, is encoded by the prion protein-encoding gene (PRNP). PrP is widely expressed in a variety of tissues and is abundant in the nervous system and participates in neuronal growth and survival. PrP expression is strongly associated with immune infiltrating cells, immunosuppressive cell infiltration and immune checkpoint molecules. PrP is an immune-related prognostic marker that holds promise for predicting outcomes related to colorectal cancer immunotherapy.