Prion protein PrP/CD230 Rekombinanter Antikörper

Prion protein PrP/CD230 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

243104D11

Kat-Nr. : 98414-4-RR

Synonyme

Prion protein PrP, PRNP, PrP, Alternative prion protein, AltPrP

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  FC experiment of human PBMCs using 98414-4-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using 98414-4-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98414-4-RR bindet in FC Prion protein PrP/CD230 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Prion protein PrP/CD230 fusion protein Eg3359
• Vollständiger Name: prion protein
• GenBank-Zugangsnummer: BC012844
• Gene symbol: PrP
• Gene ID (NCBI): 5621
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

The major prion protein (PrP), also known as CD230, is encoded by the prion protein-encoding gene (PRNP). PrP is widely expressed in a variety of tissues and is abundant in the nervous system and participates in neuronal growth and survival. PrP expression is strongly associated with immune infiltrating cells, immunosuppressive cell infiltration and immune checkpoint molecules. PrP is an immune-related prognostic marker that holds promise for predicting outcomes related to colorectal cancer immunotherapy.