Prokineticin 1 Polyklonaler Antikörper

Prokineticin 1 Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15152-1-PBS

Synonyme

PROK1, EG VEGF, EGVEGF, EG-VEGF, Endocrine-gland-derived vascular endothelial growth factor

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  IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 15152-1-AP (same clone as 15152-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

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  IF Staining of NIH/3T3 using 15152-1-AP (same clone as 15152-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed NIH/3T3 cells using Prokineticin 1 antibody (15152-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

15152-1-PBS bindet in IHC, IF/ICC, Indirect ELISA Prokineticin 1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Prokineticin 1 fusion protein Ag5098
• Vollständiger Name: prokineticin 1
• Berechnetes Molekulargewicht: 12 kDa
• GenBank-Zugangsnummer: BC025399
• Gene symbol: Prokineticin 1
• Gene ID (NCBI): 84432
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Prokineticin 1 (PROK1) is also named as EG-VEGF and Mambakine, belongs to the to the AVIT (prokineticin) family. Prokineticin signaling comprises two secreted proteins (Prok-1 and Prok-2) and two cognate G-protein coupled receptors (PK-R1 and PK-R2) that are widely expressed in different tissues and of great versatility. Prokineticins were shown to promote angiogenesis in steroidgenic glands, heart and reproductive organs (PMID:18440852). PROK1 has been described as a secretory protein with pleiotropic functions and as a novel tissue-specific angiogenic factor (PMID:32355954). EG-VEGF/PK-1, described as selective angiogenic mitogen, is widely expressed in different tissues including steroidogenic endocrine glands (PMID:16320832). A lot of data suggests EG-VEGF to be restricted to endocrine glands and to some endocrine-dependent organs (PMID:28386275).