Prothymosin Alpha Polyklonaler Antikörper

Prothymosin Alpha Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10480-1-PBS

Synonyme

Prothymosin alpha, N-terminally processed, prothymosin, alpha, PTMA, Thymosin alpha-1

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  IHC staining of human thyroid cancer using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 10480-1-AP (Prothymosin Alpha antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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  IHC staining of rat colon using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat colon tissue slide using 10480-1-AP (Prothymosin Alpha antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

10480-1-PBS bindet in IHC, Indirect ELISA Prothymosin Alpha und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Prothymosin Alpha fusion protein Ag0732
• Vollständiger Name: prothymosin, alpha
• Berechnetes Molekulargewicht: 12 kDa
• GenBank-Zugangsnummer: BC003510
• Gene symbol: Prothymosin Alpha/PTMA
• Gene ID (NCBI): 5757
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.

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