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- KD/KO Validated
QKI Polyklonaler Antikörper
QKI Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IP, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 13169-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
13169-1-PBS bindet in WB, IHC, IP, Indirect ELISA QKI und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | QKI fusion protein Ag3822 |
| Vollständiger Name | quaking homolog, KH domain RNA binding (mouse) |
| Berechnetes Molekulargewicht | 341 aa, 38 kDa |
| Beobachtetes Molekulargewicht | 38 kDa |
| GenBank-Zugangsnummer | BC019917 |
| Gene symbol | QKI |
| Gene ID (NCBI) | 9444 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
QKI (Quaking) is RNA-binding protein that plays a central role in myelinization (PMID: 16641098). It regulates pre-mRNA splicing, mRNA export and protein translation (PMID: 16641098). It acts upstream of or within several processes, including long-chain fatty acid biosynthetic process, positive regulation of macromolecule metabolic process and vasculogenesis. QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism. It is expressed in the frontal cortex of brain (PMID: 16342280).





