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QSER1 Polyklonaler Antikörper

QSER1 Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55326-1-PBS

Synonyme

glutamine and serine rich 1

Filter:
  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using QSER1 Polyclonal antibody (55326-1-AP)

    IHC staining of human pancreas cancer using 55326-1-AP (same clone as 55326-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 55326-1-AP (QSER1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55326-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using QSER1 Polyclonal antibody (55326-1-AP)

    IHC staining of human pancreas cancer using 55326-1-AP (same clone as 55326-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 55326-1-AP (QSER1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55326-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using QSER1 Polyclonal antibody (55326-1-AP)

    IF Staining of HeLa using 55326-1-AP (same clone as 55326-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using QSER1 antibody (55326-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 55326-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55326-1-PBS bindet in IHC, IF/ICC, Indirect ELISA QSER1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name glutamine and serine rich 1
Berechnetes Molekulargewicht 190 kDa
GenBank-ZugangsnummerNM_001076786
Gene symbol QSER1
Gene ID (NCBI) 79832
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

QSER1, a recently characterized protein, whose activity has been tightly associated with the protection of DNA methylation sites in hESCs. QSER1 is widely up-regulated in multiple cancers, and its up-regulation correlates with poor clinic outcomes (PMID: 36371602). QSER1 depletion leads to NODAL de-repression and associates with increased RNA Polymerase II occupancy at YAP1bound enhancers, pointing to a QSER1 contribution maintaining low transcriptional activity on certain genomic regions (PMID: 33833093, 35210841).