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QSOX1/Quiescin Q6 Rekombinanter Antikörper

QSOX1/Quiescin Q6 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240946B11

Kat-Nr. : 83952-3-PBS

Synonyme

QSOX1, QSCN6, Q6, hQSOX, EC:1.8.3.2

Filter:
  • Western Blot (WB) analysis of various lysates using QSOX1/Quiescin Q6 Recombinant antibody (83952-3-RR)

    WB analysis using 83952-3-RR (same clone as 83952-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83952-3-RR (QSOX1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83952-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

83952-3-PBS bindet in WB, ELISA QSOX1/Quiescin Q6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen QSOX1/Quiescin Q6 fusion protein Ag3396
Vollständiger Name quiescin Q6 sulfhydryl oxidase 1
Berechnetes Molekulargewicht 747 aa, 83 kDa
Beobachtetes Molekulargewicht 66-83kDa
GenBank-ZugangsnummerBC017692
Gene symbol QSOX1
Gene ID (NCBI) 5768
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

QSOX1(Sulfhydryl oxidase 1) catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.It has two isoforms with the molecular weight of 67 kda and 83 kDa,respectively. It is detected a band of 95 Kda in HT1080 cell lines (PMID:17331072).Isoform 1 is expressed on golgi apparatus membrane and isoform 2 is secreted (PMID:10708601). The isoform1(QSOX1a) is the full length of QSOX1, approximately 78 kd; and the isoform2(QSOX1b) is the splicing form, approximately 62kd(PMID:14633699; 2496424). QSOX1 is highly expressed in tumor cell lines but is not expressed in adjacent normal cells (PMID:21989104).