• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
  • Featured Product
  • KD/KO Validated

QTRT1 Polyklonaler Antikörper

QTRT1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12349-1-PBS

Synonyme

EC:2.4.2.64, FP3235, Guanine insertion enzyme, Queuine tRNA-ribosyltransferase catalytic subunit 1, TGT

Filter:
  • Western Blot (WB) analysis of HeLa cells using QTRT1 Polyclonal antibody (12349-1-AP)

    WB analysis of HeLa using 12349-1-AP (same clone as 12349-1-PBS)

    WB result of QTRT1 antibody (12349-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-QTRT1 transfected HeLa cells. This data was developed using the same antibody clone with 12349-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12349-1-PBS bindet in WB, Indirect ELISA QTRT1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen QTRT1 fusion protein Ag3010
Vollständiger Name queuine tRNA-ribosyltransferase 1
Berechnetes Molekulargewicht 403 aa, 44 kDa
Beobachtetes Molekulargewicht 44 kDa
GenBank-ZugangsnummerBC015350
Gene symbol QTRT1
Gene ID (NCBI) 81890
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

QTRT1 (Queuine tRNA-ribosyltransferase catalytic subunit 1), also known as tRNA-guanine transglycosylase (TGT), is a key enzymeinvolved in the post-transcriptional modification of tRNAs. In humans, the QTRT1 and QTRT2 heterodimer complex exhibits transglycosylase activity, and replaces the guanine base of the first letter of the tRNA anticodon with q, thus forming Q on the tRNA (PMID: 30149595, 25884661). High QTRT1 expression is a biomarkerfor poor prognosis in LUAD patients, and QTRT1 mayfunction as a latent tumor biomarker in the prognosticprediction for LUAD (PMID: 33490170).