RAB12 Rekombinanter Antikörper

RAB12 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251398D2

Kat-Nr. : 86560-1-PBS

Synonyme

Ras related protein Rab 12, Ras-related protein Rab-12

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  WB analysis using 86560-1-RR (same clone as 86560-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86560-1-RR (RAB12 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86560-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86560-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86560-1-RR against Human RAB12 were performed. The affinity constant is 0.200 nM.

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Geprüfte Anwendungen

Produktinformation

86560-1-PBS bindet in WB, Indirect ELISA RAB12 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: RAB12 fusion protein Ag31627
• Vollständiger Name: RAB12, member RAS oncogene family
• Berechnetes Molekulargewicht: 27KD
• Beobachtetes Molekulargewicht: 27 kDa
• GenBank-Zugangsnummer: NM_001025300
• Gene symbol: RAB12
• Gene ID (NCBI): 201475
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RAB12 belongs to the small GTPase superfamily and Rab family. RAB12 locates in Golgi apparatus membrane. Rab12, a previously uncharacterized Rab isoform, is mainly localized at TfR-positive recycling endosomes and is specifically involved in TfR degradation. Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes.