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RAB17 Polyklonaler Antikörper

RAB17 Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17501-1-PBS

Synonyme

Ras-related protein Rab-17, Ras related protein Rab 17

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  • Immunohistochemistry (IHC) staining of human pancreas tissue using RAB17 Polyclonal antibody (17501-1-AP)

    IHC staining of human pancreas using 17501-1-AP (same clone as 17501-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 17501-1-AP (RAB17 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17501-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human pancreas tissue using RAB17 Polyclonal antibody (17501-1-AP)

    IHC staining of human pancreas using 17501-1-AP (same clone as 17501-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 17501-1-AP (RAB17 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17501-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of WIF-B cells using RAB17 Polyclonal antibody (17501-1-AP)

    IF Staining of WIF-B cells using 17501-1-AP (same clone as 17501-1-PBS)

    IF result of RAB17 antibody (17501-1-AP) with WIF-B cells overexpressed myc-tagged RAB17 by A.C. Striz and Dr. P.L. Tuma. This data was developed using the same antibody clone with 17501-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17501-1-PBS bindet in IHC, IF/ICC, Indirect ELISA RAB17 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RAB17 fusion protein Ag11688
Vollständiger Name RAB17, member RAS oncogene family
Berechnetes Molekulargewicht 212 aa, 23 kDa
GenBank-ZugangsnummerBC050426
Gene symbol RAB17
Gene ID (NCBI) 64284
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RAB17 is a member of the RAS oncogene family and is classified as a small GTPase that plays a crucial role in intracellular membrane trafficking It is specifically expressed in epithelial cells and is involved in various cellular functions such as transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. This process is mainly observed in epithelial cells and is important for the transcellular transport of substances like immunoglobulins from the basolateral surface to the apical surface. RAB17 is also implicated in the regulation of melanosome transport and release from melanocytes, which is critical for pigmentation in skin cells . Additionally, it has been suggested to regulate dendrite and dendritic spine development, which are important for neuronal function. The protein is involved in membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis.